翻訳と辞書
Words near each other
・ DNA polymerase
・ DNA polymerase alpha
・ DNA polymerase alpha catalytic subunit
・ DNA polymerase alpha subunit 2
・ DNA polymerase beta
・ DNA polymerase delta
・ DNA polymerase epsilon
・ DNA polymerase eta
・ DNA polymerase I
・ DNA polymerase II
・ DNA polymerase III holoenzyme
・ DNA polymerase IV
・ DNA polymerase lambda
・ DNA polymerase mu
・ DNA polymerase nu
DNA polymerase V
・ DNA Productions
・ DNA profiling
・ DNA profiling (disambiguation)
・ DNA Publications
・ DNA re-replication
・ DNA read errors
・ DNA repair
・ DNA Repair (journal)
・ DNA Repair and Mutagenesis
・ DNA repair and recombination protein RAD54-like
・ DNA repair protein XRCC4
・ DNA repair-deficiency disorder
・ DNA replication
・ DNA replication factor CDT1


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DNA polymerase V : ウィキペディア英語版
DNA polymerase V

DNA polymerase V is a prokaryotic polymerase. that is involved in SOS response and translesion synthesis DNA repair mechanisms.It is related to DNA Polymerase IV, being both of them Y-family DNA polymerases that are involved in SOS response and translesion synthesis DNA repair mechanisms. Transcription of Pol V via the umuDC genes is highly regulated to produce only Pol V when damaged DNA is present in the cell generating an SOS response. Stalled polymerases causes RecA to bind to the ssDNA, which causes the LexA protein to autodigest. LexA then loses is ability to repress the transcription of the umuDC operon. The same RecA-ssDNA nucleoprotein posttranslationally modifies the UmuD protein into UmuD' protein. ≈UmuD and UmuD' form a heterodimer that interacts with UmuC, which in turn activates umuC's polymerase catalytic activity on damaged DNA.
== References ==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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